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Our luxurious progesterone cream contains real USP micronized progesterone - 500 mg per ounce - in a silky cream base.

What is Natural Progesterone Cream?

For the last 30 years, Dr. John Lee has been advocating the use of progesterone cream in menopausal and pre-menopausal women. Unfortunately, Dr. Lee passed away, but his legacy and his knowledge are still alive. We decided to develop our Natural Progesterone Cream based on Dr. Lee?s research.

Our luxurious progesterone cream contains real USP micronized progesterone ? 500 mg per ounce ? in a silky cream base.

We also offer other progesterone supplements, such as Natural Progesterone Gel and Healthy Progesterone Cream, two great Progesterone supplements.

What does Natural Progesterone Cream do?

Women throughout the world are becoming better acquainted with the health benefits of natural progesterone. Natural Progesterone reduces the symptoms and discomfort of Menopause, PMS and Premenopause without the side effects often associated with synthetic hormone replacement therapy.

Do not confuse Natural Progesterone with dangerous progestins hyped by the pharmaceutical industry. We refer only to wholly natural progesterone exactly like your body produces in abundant quantities during pregnancy.

Dr. John Lee's best selling book lists the following benefits of Natural Progesterone:

  • Restores sex drive
  • Protects against fibrocystic breasts
  • Natural antidepressant
  • Facilitates thyroid hormone action
  • Normalizes blood sugar levels
  • Normalizes zinc and copper levels
  • Helps prevent breast cancer
  • Helps the body use fat for energy
  • Improves sleep patterns
  • Normalizes blood clotting
  • Restores proper oxygen cell levels
  • Natural diuretic
  • Helps eliminate depression after child birth

What is Menopause?

Menopause is normally defined as the end of menstrual cycles. The unpleasant symptoms of menopause that some women suffer, such as hot flashes, vaginal dryness, and mood swings are peculiar to western industrialized societies. Menopause is often associated with the end of a woman?s sexuality and the beginning of old age, and arthritis, but it doesn?t have to be that way!

What does Progesterone have to do with Menopause?

A woman's ovaries make two hormones: estrogen and progesterone. When these hormones are out of balance, hormone related illnesses can emerge. Due to ovulatory cycles, progesterone levels typically decline before menopause starts, which is in turn followed by a decline in estrogen. Progesterone production tends to fall to almost zero while estrogen declines to about 40% to 50%. This situation leads to an imbalance between estrogen and progesterone causing an increase in estrogen activity, something now described as estrogen dominance.

What is Estrogen Dominance?

It is clear that estrogen, when unopposed or unbalanced by progesterone, is not something to be desired. Stated differently, many of estrogen's undesirable side effects are effectively prevented by progesterone. Dr. Lee has named this syndrome Estrogen Dominance. This syndrome occurs mostly in industrialized countries and commonly occurs in the following situations:

  • When women are on estrogen replacement therapy;
  • During premenopause, when early follicle depletion results in the lack of ovulation and thus a lack of progesterone well before the onset of menopause;
  • Exposure to xenoestrogens, which is the cause of early follicle depletion. Xenoestrogens are foreign substances found outside the body in the air, food, and environment that have an estrogen-like effect on the body;
  • Taking birth control pills with an excessive estrogen component;
  • Women who have had a hysterectomy leading to dysfunction of the ovaries;
  • Post-menopause, especially in overweight women

The following are some of the symptoms that can be caused or made worse by estrogen dominance:

  • Osteoporosis
  • Allergies
  • Fatigue
  • Fat gain
  • Memory loss
  • Uterine cancer
  • Hypoglycemia
  • Uterine fibroids
  • Fibrocystic breasts,
  • Breast tenderness
  • Decreased sex drive
  • PMS
  • Gallbladder disease
  • Miscarriage
  • Acceleration of aging
  • Depression
  • Headaches
  • Irritability
  • Infertility
  • Foggy thinking
  • Increased risk of strokes

Osteoporosis and Progesterone

Osteoporosis is an unnecessary but epidemic affliction that is perpetuated by two myths. The first is that it is caused by calcium deficiency. This is not true as women in Western industrialized countries who take in the most calcium are the most afflicted. The second myth is that osteoporosis is due to low estrogen levels and that taking horse estrogens will solve the problem. Actually, bone loss in American women starts at age 40, when they have an abundance of estrogen. In fact, osteoporosis occurs when progesterone levels fall due to increasing anovulation.

Progesterone Supplementation

Many women find that by supplementing their hormone production with natural progesterone they will reduce many or most of their menopausal symptoms. The presence of progesterone in the body sensitizes estrogen receptor sites thus enabling estrogen to work more efficiently. Progesterone is a precursor to other hormones in the body including estrogen, testosterone, and especially the corticosteroids.

Progesterone is one of two main hormones, the other being estrogen, made by the ovaries of menstruating women. Progesterone is also made in smaller amounts by the adrenal glands in both sexes and by the testes in males. When a woman's monthly cycle is functioning correctly, estrogen is the dominant hormone during the first two weeks of the menstrual cycle. In response to ovulation, progesterone assumes dominance for the final two weeks of the month. When the pituitary gland in the brain sends a message to the ovaries to stop production of progesterone, the menstrual cycle begins within 48 hours of this message.

Every body is different. That?s why we recommend testing your hormone levels to find out how much progesterone supplementation your body needs. We offer home-testing kits for 2 Hormones, so that you can feel safe in administering the correct amount of progesterone for your specific needs. Additional hormones can be added to the test for an extra fee payable directly to the testing lab.

Supplement Spot?s Natural Progesterone Cream offers safe, gentle relief from your Estrogen Dominance symptoms while moisturizing your skin with natural oils. With our 30-day money back guarantee, you have nothing to lose but your pain and discomfort!

What the Experts say about Natural Progesterone Creams

There are some great books on menopause written by physicians. Here are some excerpts from prominent authors whose books are great resources for women wanting to educate themselves about natural options for dealing with menopause.

"There are many approaches to cooling hot flashes...A progesterone skin cream works in about 85% of perimenopausal women; The Wisdom of Menopause, Christiane Northrup, MD , 2001, p 125

"...Since the postmenopausal woman continues to make estrogen in respectable levels and makes little or no progesterone, hot flashes may well respond to progesterone supplementation alone ? The vast majority of menopausal problems can be avoided by good nutrition, avoidance of toxins, regular exercise and the proper supplementation, when indicated for hormone balance, of real, honest-to-God, natural progesterone." What Your Doctor May Not Tell You About Menopause, John Lee, MD, 1996, pgs. 122 and 128

"Due to months or years of irregular ovulation in the perimenopausal years, our production of progesterone is the initial hormone that declines, not estrogen? This relative progesterone deficiency explains many of the perimenopausal changes such as mood swings, hot flashes, vaginal dryness, and irregular menses. The goal of natural progesterone cream is to support the waning daily production of progesterone in the body and accomplish physiologic levels of progesterone." Women's Encyclopedia of Natural Medicine, Tori Hudson, ND, 1999, p. 165

"Imbalanced hormone levels contribute to so-called menstrual migraines during perimenopause and menopause. This type of headache usually comes just before your period, when both estrogen and progesterone levels can fall dramatically. Hundreds of women have been able to completely recover from menstrual and menopausal migraines through the use of progesterone cream. Apply - tsp on your skin daily for the two weeks prior to your period, or three weeks out of every month if you're no longer having periods." The Wisdom of Menopause, Christiane Northrup, MD , 2001, p 127

"In most cases the symptoms are eliminated. I have not encountered any substance which is more effective than progesterone in relieving PMS." - Dr. Louis Marx, Psychiatrist (From Dr John Lee's Medical Letter)


Distilled Water, Grapeseed Oil, Sunflower Oil, Glyceryl Stearate, Glycerine, Cetearyl Glucoside, DMDM Hydantoin, 500 mg per oz USP Progesterone, Palmitoyl Pentapeptide-3, Xantham Gum, Caprylic Acid, Glycine, Potassium Sorbate, Tocopherol, Iodopropynyl Carbamate


Suggested Use: Apply to soft areas such as the inner arms, chest, or neck. Rotate application area daily to avoid saturation.

Pre-menopausal women: Apply 1-2 pumps twice a day, 14 days before expected menses, discontinue use 1-2 days before menses and start again 10-12 days after menses (counting the first day of menstruation as Day 1).

Post-menopausal women: Apply 1-2 pumps twice a day for 25 consecutive days and discontinue use for 5 consecutive days.

Each full press of the pump dispenses about 17 mg progesterone.


For external use only. Do not use on sores or wounds. Discontinue use of irritation develops. Avoid contact with eyes.

As always, consult your physician before using this product, especially if you have a medical or psychiatric condition, or are pregnant or lactating.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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$28.95 Reg.
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